The association between heavy, long-term smoking and lung problems has been recognized for over one hundred and fifty years. As early as the 1860s, physicians were warning folks about the effects of smoking on the lungs and breathing. Modern research has only served to make that link clearer and more well-founded.
Over four thousand chemicals in cigarette smoke are potentially harmful although not all are present in significant amounts. However, nicotine and other known cancer-causing compounds, known as carcinogens are. Several of them, under the heat of combustion of the tobacco leaves, bind together to form tar, a known lung-injuring compound.
Effects of Smoking on the Respiratory System
Tar acts in two ways to produce stress on various parts of the lungs. Because of its sticky nature, it clings to cilia, the short, hair-like structures that line the airways, also known as bronchi and bronchioles.
Mucus producing cells in the airways are stimulated when irritants contact them. The mucus traps smoke, dust, and small organisms and the cilia move upward in a coordinated way to push that phlegm back up the passages. From there, natural muscular action coughs it up, spits it out, or swallows it.
Tar hinders the ability of cilia to perform that function. At the same time, other chemicals stimulate excess production of mucus, making it harder for the already-weakened cilia to operate. Other chemicals in cigarette and cigar smoke contribute to the breakdown of those natural clearing mechanisms. Pipe smoke will as well, but it is less likely to be inhaled, and hence tends to affect the throat, tongue, and lips more than the airways.
At the same time, tar and other substances from smoke tend to migrate far down into the lungs, ultimately reaching the end-points: the alveoli. These are the tiny sacs at the terminus of the bronchioles that exchange CO2 out of and oxygen into the bloodstream. That exchange is the primary function of breathing.
The mere physical presence of tar particles tends to interrupt the function of the alveoli, since they occupy space that would otherwise contain air or CO2. In addition, several compounds in cigarette smoke tend to weaken the walls of the alveoli and otherwise damage their natural function.
Long Term Effects of Smoking in the Lungs

Diagram showing difference between a healthy lung and that of a tobacco smoker
Over time, the effects of smoking builds up as can be seen by the black stains visible on a smoker’s lungs. Gradually, lung capacity is reduced. Over a period of years, the chemicals continue to injure all the parts of the lung and airways, representing a major risk factor for COPD, including chronic bronchitis and emphysema, as well as other lung diseases.
The odds of a long-term, pack-a-day smoker contracting these conditions are about ten times higher than a person who never smoked. Fortunately, quitting now can reduce your odds of disease to near the levels of a non-smoker. After about five years of non-smoking, your chances of contracting lung cancer, for example, are only somewhat higher than those of a smoker.