Peyronie's disease is somewhat of a mystery to medical researchers although some doctors firmly believe that it develops, in part, because of micro-traumas to the inner lining of the penis. Such things as hitting or injuring the pelvic region could cause such damage although the majority of men with the condition are normally unable to recall any such traumatic events. A relatively rare condition affecting around one percent of the male population, its onset tends to be around middle age, although men of any age may be afflicted. In many cases, Peyronies manifests itself in patients with no history of trauma while other cases to develop slowly over many years with no apparent reason.

There are a several underlying causes that can make diagnosing and treating erectile dysfunction somewhat difficult. Some are temporary, such as the occasional excess use of alcohol, in which case the impotence is not labeled as ED. However, in other cases, it is the result of some long-term diseases, such as diabetes or Parkinson's. disease.